Research
I study how the human brain supports complex cognition — from abstract reasoning and rule learning to the effects of sleep on neural and fluid dynamics. My work combines functional neuroimaging, network science, and computational modeling.
Dopamine, Aging, & Alzheimer's Disease
Age-related shifts in the dopamine system shape memory and cognition. We use multimodal brain imaging and network science approaches to investigate the neurochemical contributions to resilience and vulnerability to age-related neurodegenerative disease including Alzheimer's disease.
Functional Brain Network Dynamics
Large-scale brain networks don't just activate - they reorganize. Graph-theoretic analyses of task-based fMRI demonstrate how the frontoparietal control network flexibly reconfigures to support rule learning, abstract reasoning, and memory-guided attention.
PET Neuroimaging for Clinical Research
PET imaging as a window into brain biology. Work spans in-human validation of new radiotracers, pharmacokinetic modeling, and comparison of drug-delivery to the brain across routes of administration.